PBPK modeling characterization of potential acute impairment effects from inhalation of ethanol during e-cigarette use.
Nonclinical
Cytotoxicity
In Vitro
More (2020)
Lung mitochondrial DNa copy number, inflammatory biomarkers, gene transcription and gene methylation in vapers and smokers.
Nonclinical
Genotoxicity
In Vitro
Mori (2022)
Does “Dry hit” vaping of vitamin E acetate contribute to EVaLI? Simulating toxic ketene formation during e-cigarette use.
Nonclinical
Respiratory Toxicity
In Vitro
Narimani (2020)
Development of an in vitro cytotoxicity model for aerosol exposure using 3D reconstructed human airway tissue; application for assessment of e-cigarette aerosol
Non-Clinical
Cytotoxicity
In Vitro
Neilson (2015)
Electronic cigarette smoke reduces ribosomal protein gene expression to impair protein synthesis in primary human airway epithelial cells.
Nonclinical
Genotoxicity
In Vitro
Park (2021)
Toxicological analysis of aerosols derived from three electronic nicotine delivery systems using normal human bronchial epithelial cells.
Nonclinical
ALL
In Vitro
Pearce (2020)
Systems toxicology-based assessment of the candidate modified risk tobacco product ThS2.2 for the adhesion of monocytic cells to human coronary arterial endothelial cells
Non-Clinical
Cardiovascular Toxicity
In Vitro
Poussin (2016)
The toxic potential of a fourth-generation E-cigarette on human lung cell lines and tissue explants.
Nonclinical
Respiratory Toxicity
In Vitro
Rankin (2019)
Transcriptomic Response of Primary human Bronchial Cells to Repeated Exposures of Cigarette and ENDS Preparations.
Nonclinical
Genotoxicity
In Vitro
Rayner (2022)
Electronic-Cigarette Use alters Nasal Mucosal Immune Response to Live-attenuated Influenza Virus.
Nonclinical
Immunotoxicity
In Vitro
Rebuli (2021)