E-cigarette aerosols containing nicotine modulate nicotinic acetylcholine receptors and astroglial glutamate transporters in mesocorticolimbic brain regions of chronically exposed mice.
Nonclinical
Safety Effects In Animals
Nicotine & Cotinine
alasmari (2021)
Effects of 3-Month Exposure to E-Cigarette aerosols on Glutamatergic Receptors and Transporters in Mesolimbic Brain Regions of Female C57BL/6 Mice.
Nonclinical
Safety Effects In Animals
Repeated-dose Toxicity
alhaddad (2020)
Subacute (28-day) toxicity of furfural in Fischer 344 rats: a comparison of the oral and inhalation route
Nonclinical
Safety Effects In Animals
Acute Toxicity
arts (2004)
In vivo assessment of the toxicity of electronic cigarettes to zebrafish (Danio rerio) embryos, following gestational exposure, in terms of mortality, developmental toxicity, and hair cell damage: Toxicity of E-cigs to zebrafish embryos.
Nonclinical
Safety Effects In Animals
Acute
Chang (2021)
Neuroinflammatory and Behavioral Outcomes Measured in adult Offspring of Mice Exposed Prenatally to E-Cigarette aerosols.
Nonclinical
Safety Effects In Animals
Acute
Church (2020)
Flavors Enhance Nicotine Vapor Self-administration in Male Mice.
Nonclinical
Safety Effects In Animals
Non-Clinical Of Nicotine & Cotinine
Cooper (2021)
Role of diabetes in lung injury from acute exposure to electronic cigarette, heated tobacco product, and combustible cigarette aerosols in an animal model.
Nonclinical
Safety Effects In Animals
Acute
Daou (2021)
Rat bronchoalveolar lavage proteome changes following e-cigarette aerosol exposures.
Nonclinical
Safety Effects In Animals
Repeat-dose
Day (2023)
E-liquids and vanillin flavoring disrupts retinoic acid signaling and causes craniofacial defects in Xenopus embryos.
Nonclinical
Safety Effects In Animals
Acute
Dickinson (2022)
Sex and age differences in approach behavior toward a port that delivers nicotine vapor.
Nonclinical
Safety Effects In Animals
Repeat-dose
Espinoza (2022)