A randomised, open-label, cross-over clinical study to evaluate the pharmacokinetic, pharmacodynamic and safety and tolerability profiles of tobacco-free oral nicotine pouches relative to cigarettes
Individual Clinical
Pharmacokinetics & Abuse Liability
ALL
Chapman (2022)
Twenty-eight day repeated exposure of human 3D bronchial epithelial model to heated tobacco aerosols indicates decreased toxicological responses compared to cigarette smoke.
Nonclinical
Respiratory Toxicity
In Vitro
Chapman (2023)
acute e-cig inhalation impacts vascular health: a study in smoking naïve subjects.
Individual Clinical
Safety
Adverse Effects
Chatterjee (2021)
Short halt in vaping modifies cardiorespiratory parameters and urine metabolome: a randomized trial.
Individual Clinical
Safety
Adverse Effects
Chaumont (2020)
Analysis and differentiation of tobacco-derived and synthetic nicotine products: Addressing an urgent regulatory issue
Non-Clinical
Chemical
Analysis
Cheetham (2022)
Electronic cigarette use and attempts to quit smoking cigarettes among adolescents in Taiwan.
Population Clinical
Cessation
Tobacco
Chen (2019)
Electronic cigarette vapour moderately stimulates pro-inflammatory signalling pathways and interleukin-6 production by human monocyte-derived dendritic cells.
Individual Clinical
Safety
Adverse Effects
Chen (2020)
Use of Electronic Cigarettes to Aid Long-Term Smoking Cessation in the United States: Prospective Evidence From the PATH Cohort Study.
Population Clinical
Cessation
Tobacco
Chen (2020)
Carbonyl Composition and Electrophilicity in Vaping Emissions of Flavored and Unflavored E-Liquids.
Nonclinical
Chemical
Analysis
Chen (2021)
Effect of e-cigarette refill liquid on follicular development and estrogen secretion in rats.
Nonclinical
Reproductive & Developmental
In Vivo
Chen (2022)